Ceftriaxone is used for Lyme disease affecting the central nervous system in children with body-weight 50 kg and over and in children aged 12 years and over, but the dose is not licensed for this indication.. Ceftriaxone: Indications. Ceftriaxone has been compared to many other antibiotics in relation to a great number of infectious diseases. In many cases it proved to be equally effective as therapies that were more expensive or potentially more dangerous.. Ceftriaxone. Ceftriaxone, sold under the trade name Rocephin, is an antibiotic useful for the treatment of a number of bacterial infections. This includes middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea,. Ceftriaxone is indicated in the treatment of the following infections in adults and children including term neonates (from birth): Bacterial Meningitis. What is ceftriaxone used for? Ceftriaxone is an antibiotic given by injection (usually in hospital) to treat serious bacterial infections such as pneumonia, septicaemia (blood poisoning . PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice.